Give it a try and see how it works for you
It is some time since I made my scanner profile and had forgotten the detail.s So I re-made it with the original raw image from the scan of the target using Vuescan.
I got a good result it seems (answered No) because I then scanned a print of some test images and the colours of the resulting image looked good on screen.
The scanner is a Canon 8400F
Terry