I bought Profile Prism with considerable skepticism, that a software program, along with a scanner that I already owned (Epson V500) could provide results that could compete with a hardware solution.  I found it a little difficult to slog through instructions (though all the needed information seems to be there), but was finally able to get all scan settings correct. The instructions are good, but didn't seem to allow for my mediocre brain. At any rate, I finally got the profile completed, and reprinted a test image.  I was amazed at the improvement (for my Epson S/P 4900) and with how perfectly the images matched.  I didn't need to do any manual editing of the profile.  I was almost disappointed not to do the editing. I'm surprised, and pleased with the product.

Fred,

 I started with Ilford Premium Photo Pearl, because I have a lot of it, and like it.  I'll next try some of the other papers I use, such as the Epson Ultra Premium Lustre.  I'm assuming I'll be able to improve on most of the canned profiles, because I'm using Jon Cone's inks,  rather than the Epson inks.

Wes