Hi Liz.
Your answer is probably one of the resets under HELP, but frankly, I shut that off many years ago as it was a PITA.
What it really did was to warn me that the profile I was attempting to use was different from the one I used last time with this setup.
I was making my own profiles at that time, and would try this new one and that routine would give me an argument.
Qimage still remembers the correct profile needed. My sure-fire method is to set everything properly, including the page orientation, and SAVE that setup under SAVE using the "P" button. Next time I want to use  Epson Ultra Luster A3 size on my Canon printer, I just click recall, "P" button, and select my saved setup.
Right paper, type and size, right profile, etc etc etc.....

Mike has added a little undocumented gem along these lines.
The recall button, just to the right of the Properties button in the Printers and settings tab is locked to the P button so you don't have to remember to click it in RECALL.
By the same token, the recall button shown as a yellow folder top left of main screen, I right click the "J" button and make it the default for that button.
So If I want to recall a Printer setup, I start at the settings screen.
If I want to recall a JOB, I use the yellow folder button top left.

I  will pass your question to Mike in case he remembers how.   

Fred

If I remember right, the monitor side of the question was determined how you set WINDOWS. You could set Windows and QU to use the sam, or notify if the profile chosen was different from the one Windows was told was default.
Where is that setting?   
I will look.
Fred

\\Hi Fred,

Hi Fred,

Yes, I understand that, my default monitor profile is in color management in the control panel. But until yesterday QU alerted me about a difference between that default profile and what QU had set;  there was an option to say "stop QU from giving me these alerts," and I inadvertently checked that option. That's the decision I want to revert so that message will appear again (hopefully without re-setting everything in QU to default).

Liz

Thanks Mike!

Liz