The spreads are 610x310mm, each file is 4-5MB.
I have 16GB of RAM in total. Printer is ipf 6350. Windows 7.
Thank you very much for the information.
I am somewhat confused as I try to re-create your set up.
In your screen snap, you show a printable area of 603.9 mm x 258.9.
You describe your spreads as 610 x 310 mm.
Obviously, 610 x 310 will not fit into a space of 603.9 x 258.9
So something is not matching up with the information.
Also in Printers and devices, check your settings, unchecking ENABLE ENHANCED, and experimenting perhaps with Start Printing immediatel, and / or print directly to printer, and see if that cures it.
Set Processor to RAW as shown in snap.
Other than that, perhaps, moving some image folders or other space consuming data to another drive, thereby freeing up more space on C:
Fred