OK I happen to have a working copy of 2010 on my desk top to help people from time to time.
I am sorry but I do not know your name.
Nevertheless, I must agree with you after 'further review".
I finally had some time to think about what you were saying over and over, and I began to recall something.
It has been many years since I used 2010.... probably 2009
One thing Qimage always had going for it was that it remembered the driver settings for next time.
I just plain forgot that.
So I went back and did some testing, and tried 6 other printer drivers. Including the Canon Pro 100, HP Z3200, Epson 4900, Epson 2000, Canon Pro 10 and Pro 1000.
I was able to reproduce what you describe, this way. (I am asking essentially, are you doing something similar?)
1) Any driver I set up in 2010 will repeat and be all sticky with the settings as it is supposed to be. That includes the Pro 100.
I can open and close 2010.210 over and over; all good.
2) In order to make 2010 lose the driver settings, I have to open Qimage Ultimate and close it. Then when I open 2010, it reverts to the checked off default printer in Printers and Devices. There, the settings for the Pro 100 are set to basics defaults, and that's what we see on the second opening of 2010.
When opening Qimage Ultimate it sees that the current settings or the Pro 100 do not match the "SAVED EXIT JOB" settings, kills the 2010 exit settings. This happens to the Epsons too; reverts to the default settings.
3) I ask if you have some other version of Qimage like the Ultimate DEMO version which was interfering, or some other printing program?
4) The work a round would be to set the quality, and the paper selection, Color management OFF and Quality setting in the Print Preferences from Devices and printers. Then that becomes the default.
Sort of tedious... but it will work.
But you were right!!
Fred