The best way to check is to make a print using each type.
Speaking of which, here's a question (not too far OT, I hope) for Qimage users: When was the last time you "tested" Qimage by printing an image with NO interpolation?
I did, recently, by accident, when I was setting up a new printer. The last setup step was a test print. I stuck some of the sample 4x6 paper in the photo tray and picked an image (about a 15% crop) which I had previously printed 8x10 on the old printer. At a quick glance, looked okay. So I printed it 8x10 so I could compare apples with apples...and was absolutely horrified at the result. Nowhere near the quality I had gotten from the old printer.
After 10 minutes of holding my head in my hands, I realized that the last thing I had printed from Qimage had been on plain paper, no interpolation, just to verify position. Re-printed using Hybrid SE and got the quality I had expected. The new print also confirmed that the HP B8550 was a distinct step up from the old Deskjet 9650...from which I got pretty good prints, using Qimage.
The difference between the no-interpolation print and the Hybrid SE print is painfully obvious. I then went back and took a closer look at the no-interpolation 4x6 test print. The difference doesn't jump off the page, as it does with the 8x10's, but it's easily visible upon close examination.
I've printed full-frame images at 8x10 with and without interpolation and have been hard-pressed to see the difference. But if you're printing large, Qimage's interpolation makes an easily-visible difference. Easy to forget that until you print without it.